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mutation medical definition

noun
  1. The act or process of being altered or changed.
  2. An alteration or change, as in nature, form, or quality.
  3. A sudden structural change within a gene or chromosome of an organism resulting in the creation of a new character or trait not found in the parental type.
  4. The process by which such a sudden structural change occurs, either through an alteration in the nucleotide sequence of the DNA coding for a gene or through a change in the physical arrangement of a chromosome.
  5. A mutant.

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