tolerance medical definition

1. Decreased responsiveness to a stimulus, especially over a period of continued exposure.
2. The capacity to absorb a drug continuously or in large doses without adverse effect; diminution in the response to a drug after prolonged use.
3. Physiological resistance to a poison.
4. Acceptance of a tissue graft or transplant without immunological rejection.
5. Unresponsiveness to an antigen that normally produces an immunological reaction.
6. The ability of an organism to resist or survive infection by a parasitic or pathogenic organism.

Related Forms:

• tolerant adjective